Activities of prenylphenol derivatives from fruitbodies of Albatrellus spp. on the human and rat vanilloid receptor 1 (VR 1) and characterisation of the novel natural product, confluentin
Several prenylphenols from basidiocarps of European and Chines Albatrellus spp., namely grifolin, neogrifolin, confluentin, scutigeral, and albaconol were investigated concerning their their activities in test models for vanilloid receptor modulation. The isolation of these compounds from A. conflue...
| Contributors: | ; ; ; ; ; ; |
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| Format: | Print Article |
| Language: | English |
| Check availability: | HBZ Gateway |
| Journals Online & Print: | Drawer...
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| Fernleihe: | Fernleihe für die Fachinformationsdienste |
| Published: |
Wiley-Blackwell
2003
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| In: |
Archiv der Pharmazie
Year: 2003, Issue: 2, Pages: 119-126 |
| Further subjects: | B
Chemistry
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| Online Access: |
PURE Lüneburg |
| Summary: | Several prenylphenols from basidiocarps of European and Chines Albatrellus spp., namely grifolin, neogrifolin, confluentin, scutigeral, and albaconol were investigated concerning their their activities in test models for vanilloid receptor modulation. The isolation of these compounds from A. confluens and structure elucidation of the novel natural product confluentin are described. The effects of scutigeral and neogrifolin on vanilloid receptors were studied by means of electrophysiological methodology on rat dorsal root ganglion neurons as well as on recombinant cell lines expressing the rat VR 1 receptor... |
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| ISSN: | 0365-6233 |
| Contains: | In: Archiv der Pharmazie
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