Destabilizing the ‘equipoise’ framework in clinical trials: prioritizing non-exploitation as an ethical framework in clinical research
The framework of equipoise has been promulgated as an underlying requirement for conducting ethical clinical research. Equipoise is the term used for a state of indifference about which treatment intervention or innovation will provide the most benefit and the least harm to recipients. Drawing on he...
| Main Author: | |
|---|---|
| Format: | Electronic Article |
| Language: | English |
| Check availability: | HBZ Gateway |
| Interlibrary Loan: | Interlibrary Loan for the Fachinformationsdienste (Specialized Information Services in Germany) |
| Published: |
2010
|
| In: |
Nursing philosophy
Year: 2010, Volume: 11, Issue: 4, Pages: 271-279 |
| Further subjects: | B
Nursing
B equipoise B clinical research B non-exploitation B Clinical trial |
| Online Access: |
Volltext (lizenzpflichtig) Volltext (lizenzpflichtig) |
MARC
| LEADER | 00000naa a22000002c 4500 | ||
|---|---|---|---|
| 001 | 1925920429 | ||
| 003 | DE-627 | ||
| 005 | 20250519102424.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 250519s2010 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1111/j.1466-769X.2010.00455.x |2 doi | |
| 035 | |a (DE-627)1925920429 | ||
| 035 | |a (DE-599)KXP1925920429 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 1 |2 ssgn | ||
| 100 | 1 | |a Schlichting, Douglas E. |e VerfasserIn |4 aut | |
| 245 | 1 | 0 | |a Destabilizing the ‘equipoise’ framework in clinical trials: prioritizing non-exploitation as an ethical framework in clinical research |
| 264 | 1 | |c 2010 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 520 | |a The framework of equipoise has been promulgated as an underlying requirement for conducting ethical clinical research. Equipoise is the term used for a state of indifference about which treatment intervention or innovation will provide the most benefit and the least harm to recipients. Drawing on healthcare, research, and ethics literature, this paper analyses the implications of equipoise from the perspective of several proponents and critics. Specifically the historical evolution of the concept based on Fried and Freedman's arguments is traced. A critique of the concept, informed by contrasting perspectives, is offered. An alternative framework of non-exploitation as presented by Miller and Brody is argued to be superior in facilitating both the ultimate goals of research on human subjects and those of the healthcare professions'. | ||
| 650 | 4 | |a clinical research | |
| 650 | 4 | |a Clinical trial | |
| 650 | 4 | |a equipoise | |
| 650 | 4 | |a non-exploitation | |
| 650 | 4 | |a Nursing | |
| 773 | 0 | 8 | |i Enthalten in |t Nursing philosophy |d Oxford [u.a.] : Wiley-Blackwell, 2000 |g 11(2010), 4, Seite 271-279 |h Online-Ressource |w (DE-627)324655436 |w (DE-600)2029286-7 |w (DE-576)093981309 |x 1466-769X |7 nnas |
| 773 | 1 | 8 | |g volume:11 |g year:2010 |g number:4 |g pages:271-279 |
| 856 | 4 | 0 | |u https://doi.org/10.1111/j.1466-769X.2010.00455.x |x Resolving-System |z lizenzpflichtig |3 Volltext |7 1 |
| 856 | 4 | 0 | |u https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1466-769X.2010.00455.x |x Verlag |z lizenzpflichtig |3 Volltext |7 1 |
| 951 | |a AR | ||
| ELC | |a 1 | ||
| ITA | |a 1 |t 1 | ||
| LOK | |0 000 xxxxxcx a22 zn 4500 | ||
| LOK | |0 001 4725730904 | ||
| LOK | |0 003 DE-627 | ||
| LOK | |0 004 1925920429 | ||
| LOK | |0 005 20250519102424 | ||
| LOK | |0 008 250519||||||||||||||||ger||||||| | ||
| LOK | |0 040 |a DE-Tue135 |c DE-627 |d DE-Tue135 | ||
| LOK | |0 092 |o n | ||
| LOK | |0 852 |a DE-Tue135 | ||
| LOK | |0 852 1 |9 00 | ||
| LOK | |0 935 |a ixzs |a ixzo |a ixrk | ||
| LOK | |0 939 |a 19-05-25 |b l01 | ||
| ORI | |a SA-MARC-ixtheoa001.raw | ||
