Xenotransplantation Clinical Trials and Equitable Patient Selection

Xenotransplant patient selection recommendations restrict clinical trial participation to seriously ill patients for whom alternative therapies are unavailable or who will likely die while waiting for an allotransplant. Despite a scholarly consensus that this is advisable, we propose to examine this...

Full description

Saved in:  
Bibliographic Details
Authors: Bobier, Christopher (Author) ; Rodger, Daniel 1985- (Author)
Format: Electronic Article
Language:English
Check availability: HBZ Gateway
Interlibrary Loan:Interlibrary Loan for the Fachinformationsdienste (Specialized Information Services in Germany)
Published: 2024
In: Cambridge quarterly of healthcare ethics
Year: 2024, Volume: 33, Issue: 3, Pages: 425-434
Further subjects:B Justice
B Ethics
B Consent
B research subjects
B Fair play
B Equity
B Clinical trial
B xenotransplantation
B allotransplantation
Online Access: Volltext (lizenzpflichtig)
Volltext (lizenzpflichtig)
Description
Summary:Xenotransplant patient selection recommendations restrict clinical trial participation to seriously ill patients for whom alternative therapies are unavailable or who will likely die while waiting for an allotransplant. Despite a scholarly consensus that this is advisable, we propose to examine this restriction. We offer three lines of criticism: (1) The risk-benefit calculation may well be unfavorable for seriously ill patients and society; (2) the guidelines conflict with criteria for equitable patient selection; and (3) the selection of seriously ill patients may compromise informed consent. We conclude by highlighting how the current guidance reveals a tension between the societal values of justice and beneficence.
ISSN:1469-2147
Contains:Enthalten in: Cambridge quarterly of healthcare ethics
Persistent identifiers:DOI: 10.1017/S096318012300052X