Religiosity and treatment response to antidepressant medication: a prospective multi-site clinical trial
The present study examined the relationship between religiosity/spirituality and treatment response to antidepressant medication (citalopram). One-hundred and forty-eight Caucasian and African-American adults with uncomplicated major depression were treated with citalopram (20-60 mg/day) over an eig...
| Authors: | ; ; ; ; ; |
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| Format: | Electronic Article |
| Language: | English |
| Check availability: | HBZ Gateway |
| Interlibrary Loan: | Interlibrary Loan for the Fachinformationsdienste (Specialized Information Services in Germany) |
| Published: |
2011
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| In: |
Mental health, religion & culture
Year: 2011, Volume: 14, Issue: 8, Pages: 805-818 |
| Further subjects: | B
Spirituality
B antidepressant B Depression B citalopram B Religiosity |
| Online Access: |
Presumably Free Access Volltext (lizenzpflichtig) |
| Summary: | The present study examined the relationship between religiosity/spirituality and treatment response to antidepressant medication (citalopram). One-hundred and forty-eight Caucasian and African-American adults with uncomplicated major depression were treated with citalopram (20-60 mg/day) over an eight-week period in a prospective multi-site clinical trial. Treatment response was assessed weekly with the Hamilton Rating Scale for Depression. Religiosity (i.e., religious behaviours) and spirituality (i.e., spiritual well-being) were assessed at week 3. No significant associations between spirituality and treatment response were found; however, there was a strong curvilinear relationship between religiosity and treatment response. Compared to lower or higher levels of religiosity, a moderate level of religiosity was significantly associated with a higher likelihood of remission and greater reduction in severity of depression. This association was independent of social support, ethnicity, gender, education, and baseline depression severity. A moderate amount of religiosity appears to be independently associated with an enhanced treatment response to citalopram. |
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| ISSN: | 1469-9737 |
| Contains: | Enthalten in: Mental health, religion & culture
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| Persistent identifiers: | DOI: 10.1080/13674676.2010.527931 |
