Patient Access to Experimental Drugs and AIDS Clinical Trial Designs: Ethical Issues

Today's clinical AIDS research is in trouble. Principal investigators are confronted with young and frequently highly knowledgeable patients. Many of these people with AIDS (PWAs) are often unwilling to adhere to the trial protocols. These PWAs believe they are ethically justified in breaching...

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Bibliographic Details
Authors: Schüklenk, Udo (Author) ; Hogan, Carlton (Author)
Format: Electronic Article
Language:English
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Published: Cambridge Univ. Press 1996
In: Cambridge quarterly of healthcare ethics
Year: 1996, Volume: 5, Issue: 3, Pages: 400-409
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Summary:Today's clinical AIDS research is in trouble. Principal investigators are confronted with young and frequently highly knowledgeable patients. Many of these people with AIDS (PWAs) are often unwilling to adhere to the trial protocols. These PWAs believe they are ethically justified in breaching trial protocols because they do not consider themselves true volunteers in such trials. PWAs argue that they do not really volunteer because existing legislation prevents them from buying and using experimental drugs or from testing alternative treatment strategies. Their only access to such agents is participation in clinical trials.
ISSN:1469-2147
Contains:Enthalten in: Cambridge quarterly of healthcare ethics
Persistent identifiers:DOI: 10.1017/S0963180100007209