Comparing Drug Effectiveness at Health Plans: The Ethics of Cluster Randomized Trials

“Cluster randomized trials,” in which groups of patients are randomly assigned to different therapeutic interventions, provide a powerful way of evaluating drugs. CRTs have not been widely used, in good part because of concerns about whether patients must give informed consent to participate in them...

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Bibliographic Details
Authors: Sabin, James E. (Author) ; Mazor, Kathleen (Author) ; Meterko, Vanessa (Author) ; Goff, Sarah L. (Author) ; Platt, Richard (Author)
Format: Electronic Article
Language:English
Check availability: HBZ Gateway
Interlibrary Loan:Interlibrary Loan for the Fachinformationsdienste (Specialized Information Services in Germany)
Published: 2008
In: The Hastings Center report
Year: 2008, Volume: 38, Issue: 5, Pages: 39-48
Online Access: Volltext (lizenzpflichtig)
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Summary:“Cluster randomized trials,” in which groups of patients are randomly assigned to different therapeutic interventions, provide a powerful way of evaluating drugs. CRTs have not been widely used, in good part because of concerns about whether patients must give informed consent to participate in them. A better understanding of how CRTs fit into clinical practice resolves the concerns.
ISSN:1552-146X
Contains:Enthalten in: Hastings Center, The Hastings Center report
Persistent identifiers:DOI: 10.1353/hcr.0.0050