Genealogical obscurement: mitochondrial replacement techniques and genealogical research

Mitochondrial replacement techniques (MRTs) are a new group of biotechnologies that aim to aid women whose eggs have disease-causing deleteriously mutated mitochondria to have genetically related healthy children. These techniques have also been used to aid women with poor oocyte quality and poor em...

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Detalhes bibliográficos
Autor principal: Palacios-González, César (Author)
Tipo de documento: Recurso Electrónico Artigo
Idioma:Inglês
Verificar disponibilidade: HBZ Gateway
Interlibrary Loan:Interlibrary Loan for the Fachinformationsdienste (Specialized Information Services in Germany)
Publicado em: 2025
Em: Journal of medical ethics
Ano: 2025, Volume: 51, Número: 3, Páginas: 219-224
Acesso em linha: Volltext (lizenzpflichtig)
Volltext (lizenzpflichtig)
Descrição
Resumo:Mitochondrial replacement techniques (MRTs) are a new group of biotechnologies that aim to aid women whose eggs have disease-causing deleteriously mutated mitochondria to have genetically related healthy children. These techniques have also been used to aid women with poor oocyte quality and poor embryonic development, to have genetically related children. Remarkably, MRTs create humans with DNA from three sources: nuclear DNA from the intending mother and father, and mitochondrial DNA from the egg donor. In a recent publication Françoise Baylis argued that MRTs are detrimental for genealogical research via mitochondrial DNA because they would obscure the lines of individual descent. In this paper, I argue that MRTs do not obscure genealogical research, but rather that MRT-conceived children can have two mitochondrial lineages. I argue for this position by showing that MRTs are reproductive in nature and, thus, they create genealogy.
ISSN:1473-4257
Obras secundárias:Enthalten in: Journal of medical ethics
Persistent identifiers:DOI: 10.1136/jme-2022-108659