Ethical analysis of the first porcine cardiac xenotransplantation

In this article, we provide an ethical analysis of the first porcine cardiac xenotransplant, performed in Maryland, USA in early 2022. David Bennett was offered the experimental procedure after he was deemed ineligible for human heart transplantation and mechanical circulatory support, based on a hi...

Ausführliche Beschreibung

Gespeichert in:  
Bibliographische Detailangaben
VerfasserInnen: Gyngell, Christopher (Verfasst von) ; Munsie, Megan (Verfasst von) ; Fujita, Misao (Verfasst von) ; Thiessen, Carrie (Verfasst von) ; Savulescu, Julian 1963- (Verfasst von) ; Konstantinov, Igor E. (Verfasst von)
Medienart: Elektronisch Aufsatz
Sprache:Englisch
Verfügbarkeit prüfen: HBZ Gateway
Fernleihe:Fernleihe für die Fachinformationsdienste
Veröffentlicht: 2024
In: Journal of medical ethics
Jahr: 2024, Band: 50, Heft: 6, Seiten: 363-367
Online-Zugang: Volltext (lizenzpflichtig)
Volltext (lizenzpflichtig)

MARC

LEADER 00000caa a22000002c 4500
001 1918777896
003 DE-627
005 20250301054334.0
007 cr uuu---uuuuu
008 250228s2024 xx |||||o 00| ||eng c
024 7 |a 10.1136/jme-2022-108685  |2 doi 
035 |a (DE-627)1918777896 
035 |a (DE-599)KXP1918777896 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 1  |2 ssgn 
100 1 |a Gyngell, Christopher  |e VerfasserIn  |4 aut 
245 1 0 |a Ethical analysis of the first porcine cardiac xenotransplantation 
264 1 |c 2024 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
520 |a In this article, we provide an ethical analysis of the first porcine cardiac xenotransplant, performed in Maryland, USA in early 2022. David Bennett was offered the experimental procedure after he was deemed ineligible for human heart transplantation and mechanical circulatory support, based on a history of non-compliance. It was reported that Mr Bennett’s previous instances of non-compliance were for medically non-life-threatening conditions years earlier, where the risks of non-compliance were not as high. We argue that, in Mr Bennett’s case, a history of non-compliance in a different context, should not necessarily rule him ineligible for a potentially life-saving treatment now. Furthermore, using previous non-compliance to exclude individuals from donor organs may have the unintended effect of placing the burden of testing xenotransplantation on those who are already disadvantaged. We then argue that it is not enough to rely on patient consent to ethically justify xenotransplantation research. Taking a broad ethical perspective is crucial when mapping a clinical pathway for xenotransplantation. 
700 1 |a Munsie, Megan  |e VerfasserIn  |4 aut 
700 1 |a Fujita, Misao  |e VerfasserIn  |0 (orcid)0000-0001-7919-5362  |4 aut 
700 1 |a Thiessen, Carrie  |e VerfasserIn  |4 aut 
700 1 |e VerfasserIn  |0 (DE-588)1163621471  |0 (DE-627)102793496X  |0 (DE-576)508091942  |4 aut  |a Savulescu, Julian  |d 1963- 
700 1 |a Konstantinov, Igor E.  |e VerfasserIn  |0 (orcid)0000-0002-9981-1123  |4 aut 
773 0 8 |i Enthalten in  |t Journal of medical ethics  |d London : BMJ Publ., 1975  |g 50(2024), 6, Seite 363-367  |h Online-Ressource  |w (DE-627)323607802  |w (DE-600)2026397-1  |w (DE-576)260773972  |x 1473-4257  |7 nnas 
773 1 8 |g volume:50  |g year:2024  |g number:6  |g pages:363-367 
856 4 0 |u https://doi.org/10.1136/jme-2022-108685  |x Resolving-System  |z lizenzpflichtig  |3 Volltext 
856 4 0 |u https://jme.bmj.com/content/50/6/363  |x Verlag  |z lizenzpflichtig  |3 Volltext 
951 |a AR 
ELC |a 1 
ITA |a 1  |t 1 
LOK |0 000 xxxxxcx a22 zn 4500 
LOK |0 001 4675095933 
LOK |0 003 DE-627 
LOK |0 004 1918777896 
LOK |0 005 20250228103858 
LOK |0 008 250228||||||||||||||||ger||||||| 
LOK |0 040   |a DE-Tue135  |c DE-627  |d DE-Tue135 
LOK |0 092   |o n 
LOK |0 852   |a DE-Tue135 
LOK |0 852 1  |9 00 
LOK |0 935   |a ixzs  |a ixzo  |a ixrk 
OAS |a 1  |b inherited from superior work 
ORI |a SA-MARC-ixtheoa001.raw