Moral Status and the Oversight of Research Involving Chimeric Animals
The use of nonhuman animals in research has long been a source of bioethical and scientific debate. We consider the oversight and use of nonhuman animals in chimeric research. We conducted interviews with twelve members of embryonic stem cell research oversight committees, nine members of institutio...
| Authors: | ; ; |
|---|---|
| Format: | Electronic Article |
| Language: | English |
| Check availability: | HBZ Gateway |
| Interlibrary Loan: | Interlibrary Loan for the Fachinformationsdienste (Specialized Information Services in Germany) |
| Published: |
2022
|
| In: |
The Hastings Center report
Year: 2022, Volume: 52, Pages: S41-S45 |
| Further subjects: | B
ESCRO committee
B Bioethics B IACUC B Humanization B ethical challenges B research oversight B chimeric research |
| Online Access: |
Volltext (kostenfrei) Volltext (kostenfrei) |
MARC
| LEADER | 00000caa a22000002c 4500 | ||
|---|---|---|---|
| 001 | 1829460439 | ||
| 003 | DE-627 | ||
| 005 | 20250304150231.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 221222s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1002/hast.1431 |2 doi | |
| 035 | |a (DE-627)1829460439 | ||
| 035 | |a (DE-599)KXP1829460439 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 1 |2 ssgn | ||
| 100 | 1 | |e VerfasserIn |0 (DE-588)1057705144 |0 (DE-627)796174490 |0 (DE-576)413155641 |4 aut |a Marshall, Patricia A. | |
| 109 | |a Marshall, Patricia A. | ||
| 245 | 1 | 0 | |a Moral Status and the Oversight of Research Involving Chimeric Animals |
| 264 | 1 | |c 2022 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 520 | |a The use of nonhuman animals in research has long been a source of bioethical and scientific debate. We consider the oversight and use of nonhuman animals in chimeric research. We conducted interviews with twelve members of embryonic stem cell research oversight committees, nine members of institutional animal care and use committees, and fourteen scientists involved in human-nonhuman-animal chimeric research in different areas of the United States. Interviews addressed animal welfare and conceptual issues associated with moral status and humanization of nonhuman animals that contain human cells. Our findings suggest that concepts of enhanced moral status and consciousness are not very useful in human-nonhuman-animal chimeric research in part because their meanings are not easily defined, which presents challenges to applying the concepts in research. Instead, scientists and oversight committee members we interviewed seemed to rely on standard assessments of changes in animal welfare when focusing on the ethics of human-animal chimeric research. | ||
| 650 | 4 | |a ESCRO committee | |
| 650 | 4 | |a IACUC | |
| 650 | 4 | |a Bioethics | |
| 650 | 4 | |a chimeric research | |
| 650 | 4 | |a ethical challenges | |
| 650 | 4 | |a Humanization | |
| 650 | 4 | |a research oversight | |
| 700 | 1 | |e VerfasserIn |0 (DE-588)1358595534 |0 (DE-627)1919059415 |4 aut |a Craig, Kaitlynn P. | |
| 700 | 1 | |e VerfasserIn |0 (DE-588)1038402298 |0 (DE-627)757245552 |0 (DE-576)39239006X |4 aut |a Hyun, Insoo |d 1970- | |
| 773 | 0 | 8 | |i Enthalten in |a Hastings Center |t The Hastings Center report |d Malden, Mass. : Wiley, 1971 |g 52(2022), S2, Seite S41-S45 |h Online-Ressource |w (DE-627)341346551 |w (DE-600)2067369-3 |w (DE-576)258761822 |x 1552-146X |7 nnas |
| 773 | 1 | 8 | |g volume:52 |g year:2022 |g supplement:S2 |g pages:S41-S45 |
| 856 | |u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hast.1431 |x unpaywall |z Vermutlich kostenfreier Zugang |h publisher [deprecated] | ||
| 856 | 4 | 0 | |u https://doi.org/10.1002/hast.1431 |x Resolving-System |z kostenfrei |3 Volltext |
| 856 | 4 | 0 | |u https://onlinelibrary.wiley.com/doi/abs/10.1002/hast.1431 |x Verlag |z kostenfrei |3 Volltext |
| 951 | |a AR | ||
| ELC | |a 1 | ||
| ITA | |a 1 |t 1 | ||
| LOK | |0 000 xxxxxcx a22 zn 4500 | ||
| LOK | |0 001 4239986982 | ||
| LOK | |0 003 DE-627 | ||
| LOK | |0 004 1829460439 | ||
| LOK | |0 005 20250304150231 | ||
| LOK | |0 008 221222||||||||||||||||ger||||||| | ||
| LOK | |0 040 |a DE-Tue135 |c DE-627 |d DE-Tue135 | ||
| LOK | |0 092 |o n | ||
| LOK | |0 852 |a DE-Tue135 | ||
| LOK | |0 852 1 |9 00 | ||
| LOK | |0 935 |a ixzs |a ixzo | ||
| OAS | |a 1 | ||
| ORI | |a SA-MARC-ixtheoa001.raw | ||
