RT Article T1 Opt-Outs and Upgrades: Ethics and Law in the United Kingdom JF Cambridge quarterly of healthcare ethics VO 23 IS 3 SP 308 OP 318 A1 Stammers, Trevor A2 James, Matt LA English YR 2014 UL https://ixtheo.de/Record/1827974729 AB We report on two areas in which UK law and ethics seem out of step with each other. 2013 saw the passing of the Human Transplantation (Wales) Bill, which will introduce an opt-out system of organ donation in Wales from 2015. In the first section, we discuss the convoluted evolution of the Bill and some potential problems that we consider may prevent it from achieving its intended goal of increasing the number of organs transplanted. The prospect of being able to enhance human cognition through cognitive-enhancing drugs (“smart drugs”) also presents a nexus of questions associated with future ambitions, hopes, and concerns as a society. How these drugs might affect the future of work and employment is beginning to generate wide public engagement in the UK and forms the focus of the second section. K1 Human Enhancement K1 modafinil K1 Ritalin K1 smart drugs K1 cognitive-enhancing drugs K1 presumed consent K1 opt out K1 Organ Transplantation K1 Organ Donation DO 10.1017/S0963180113000911