Drug Repurposing for COVID-19: Ethical Considerations and Roadmaps

While the world rushed to develop treatments for COVID-19, some turned hopefully to drug repurposing (drug repositioning). However, little study has addressed issues of drug repurposing in emergency situations from a broader perspective, taking into account the social and ethical ramifications. When...

Full description

Saved in:  
Bibliographic Details
Authors: Ino, Hiroyasu (Author) ; Nakazawa, Eisuke (Author) ; Akabayashi, Akira (Author)
Format: Electronic Article
Language:English
Check availability: HBZ Gateway
Journals Online & Print:
Drawer...
Fernleihe:Fernleihe für die Fachinformationsdienste
Published: Cambridge Univ. Press 2021
In: Cambridge quarterly of healthcare ethics
Year: 2021, Volume: 30, Issue: 1, Pages: 51-58
Further subjects:B drug repurposing
B Covid-19
B resource distribution
B drug repositioning
Online Access: Volltext (kostenfrei)
Volltext (kostenfrei)
Description
Summary:While the world rushed to develop treatments for COVID-19, some turned hopefully to drug repurposing (drug repositioning). However, little study has addressed issues of drug repurposing in emergency situations from a broader perspective, taking into account the social and ethical ramifications. When drug repurposing is employed in emergency situations, the fairness of resource distribution becomes an issue that requires careful ethical consideration.This paper examines the drug repurposing in emergency situations focusing on the fairness using Japanese cases. Ethical issues under these circumstances addressed by the authors include: maintaining the evidence level, integrity of clinical research ethics, and voluntary consent by original indication patients. In order to address these issues, they argue that rapid accumulation of ethically and scientifically valid evidence is required, as is obtaining information on resource quantity.
ISSN:1469-2147
Contains:Enthalten in: Cambridge quarterly of healthcare ethics
Persistent identifiers:DOI: 10.1017/S0963180120000481