Fetal Repair of Open Neural Tube Defects: Ethical, Legal, and Social Issues
Open neural tube defects or myelomeningoceles are a common congenital condition caused by failure of closure of the neural tube early in gestation, leading to a number of neurologic sequelae including paralysis, hindbrain herniation, hydrocephalus and neurogenic bowel and bladder dysfunction. Tradit...
| Authors: | ; ; |
|---|---|
| Format: | Electronic Article |
| Language: | English |
| Check availability: | HBZ Gateway |
| Journals Online & Print: | Drawer...
|
| Fernleihe: | Fernleihe für die Fachinformationsdienste |
| Published: |
Cambridge Univ. Press
2019
|
| In: |
Cambridge quarterly of healthcare ethics
Year: 2019, Volume: 28, Issue: 3, Pages: 476-487 |
| Further subjects: | B
myelomeningocele
B surgical innovation B fetal surgery |
| Online Access: |
Volltext (lizenzpflichtig) Volltext (lizenzpflichtig) |
MARC
| LEADER | 00000naa a22000002 4500 | ||
|---|---|---|---|
| 001 | 1827971207 | ||
| 003 | DE-627 | ||
| 005 | 20221220052638.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 221220s2019 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1017/S0963180119000409 |2 doi | |
| 035 | |a (DE-627)1827971207 | ||
| 035 | |a (DE-599)KXP1827971207 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 1 |2 ssgn | ||
| 100 | 1 | |a Radic, Julia a. E. |e VerfasserIn |4 aut | |
| 245 | 1 | 0 | |a Fetal Repair of Open Neural Tube Defects: Ethical, Legal, and Social Issues |
| 264 | 1 | |c 2019 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 520 | |a Open neural tube defects or myelomeningoceles are a common congenital condition caused by failure of closure of the neural tube early in gestation, leading to a number of neurologic sequelae including paralysis, hindbrain herniation, hydrocephalus and neurogenic bowel and bladder dysfunction. Traditionally, the condition was treated by closure of the defect postnatally but a recently completed randomized controlled trial of prenatal versus postnatal closure demonstrated improved neurologic outcomes in the prenatal closure group. Fetal surgery, or more precisely maternal-fetal surgery, raises a number of ethical issues that we address including who the patient is, informed consent, surgical innovation and equipoise as well maternal assumption of risk. As the procedure becomes more widely adopted into practice, we suggest close monitoring of new fetal surgery centers, in order to ensure that the positive results of the trial are maintained without increased risk to both the mother and fetus. | ||
| 650 | 4 | |a surgical innovation | |
| 650 | 4 | |a fetal surgery | |
| 650 | 4 | |a myelomeningocele | |
| 700 | 1 | |a Illes, Judy |e VerfasserIn |4 aut | |
| 700 | 1 | |a Mcdonald, Patrick J. |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Cambridge quarterly of healthcare ethics |d Cambridge : Cambridge Univ. Press, 1992 |g 28(2019), 3, Seite 476-487 |h Online-Ressource |w (DE-627)306655039 |w (DE-600)1499985-7 |w (DE-576)081985010 |x 1469-2147 |7 nnns |
| 773 | 1 | 8 | |g volume:28 |g year:2019 |g number:3 |g pages:476-487 |
| 856 | 4 | 0 | |u https://doi.org/10.1017/S0963180119000409 |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://www.cambridge.org/core/journals/cambridge-quarterly-of-healthcare-ethics/article/fetal-repair-of-open-neural-tube-defects-ethical-legal-and-social-issues/0016262C5E58A144F04146FEFA16C844 |x Verlag |z lizenzpflichtig |3 Volltext |
| 935 | |a mteo | ||
| 936 | u | w | |d 28 |j 2019 |e 3 |h 476-487 |
| 951 | |a AR | ||
| ELC | |a 1 | ||
| ITA | |a 1 |t 1 | ||
| LOK | |0 000 xxxxxcx a22 zn 4500 | ||
| LOK | |0 001 423537611X | ||
| LOK | |0 003 DE-627 | ||
| LOK | |0 004 1827971207 | ||
| LOK | |0 005 20221220052638 | ||
| LOK | |0 008 221220||||||||||||||||ger||||||| | ||
| LOK | |0 035 |a (DE-Tue135)IxTheo#2022-12-06#AEE43BBFA47F36AB019668599DB87C88F4D3F860 | ||
| LOK | |0 040 |a DE-Tue135 |c DE-627 |d DE-Tue135 | ||
| LOK | |0 092 |o n | ||
| LOK | |0 852 |a DE-Tue135 | ||
| LOK | |0 852 1 |9 00 | ||
| LOK | |0 935 |a ixzs |a ixrk |a zota | ||
| ORI | |a SA-MARC-ixtheoa001.raw | ||