Principles of Early Stopping of Randomized Trials for Efficacy: A Critique of Equipoise and an Alternative Nonexploitation Ethical Framework
, Recent controversial decisions to terminate several large clinical trials have called attention to the need for developing a sound ethical framework to determine when trials should be stopped in light of emerging efficacy data. Currently, the fundamental rationale for stopping trials early is base...
Authors: | ; |
---|---|
Format: | Electronic Article |
Language: | English |
Check availability: | HBZ Gateway |
Journals Online & Print: | |
Fernleihe: | Fernleihe für die Fachinformationsdienste |
Published: |
Johns Hopkins Univ. Press
2005
|
In: |
Kennedy Institute of Ethics journal
Year: 2005, Volume: 15, Issue: 2, Pages: 161-178 |
Online Access: |
Volltext (lizenzpflichtig) Volltext (lizenzpflichtig) |