Comprehension of a simplified assent form in a vaccine trial for adolescents
Introduction Future HIV vaccine efficacy trials with adolescents will need to ensure that participants comprehend study concepts in order to confer true informed assent. A Hepatitis B vaccine trial with adolescents offers valuable opportunity to test youth understanding of vaccine trial requirements...
| Authors: | ; ; ; ; ; ; ; ; ; ; |
|---|---|
| Format: | Electronic Article |
| Language: | English |
| Check availability: | HBZ Gateway |
| Journals Online & Print: | Drawer...
|
| Fernleihe: | Fernleihe für die Fachinformationsdienste |
| Published: |
BMJ Publ.
2013
|
| In: |
Journal of medical ethics
Year: 2013, Volume: 39, Issue: 6, Pages: 410-412 |
| Online Access: |
Presumably Free Access Volltext (JSTOR) Volltext (lizenzpflichtig) Volltext (lizenzpflichtig) |
MARC
| LEADER | 00000caa a22000002 4500 | ||
|---|---|---|---|
| 001 | 1816146196 | ||
| 003 | DE-627 | ||
| 005 | 20230427161314.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 220908s2013 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1136/medethics-2012-101286 |2 doi | |
| 035 | |a (DE-627)1816146196 | ||
| 035 | |a (DE-599)KXP1816146196 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 1 |2 ssgn | ||
| 100 | 1 | |a Lee, Sonia |e VerfasserIn |4 aut | |
| 245 | 1 | 0 | |a Comprehension of a simplified assent form in a vaccine trial for adolescents |
| 264 | 1 | |c 2013 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 520 | |a Introduction Future HIV vaccine efficacy trials with adolescents will need to ensure that participants comprehend study concepts in order to confer true informed assent. A Hepatitis B vaccine trial with adolescents offers valuable opportunity to test youth understanding of vaccine trial requirements in general. Methods Youth reviewed a simplified assent form with study investigators and then completed a comprehension questionnaire. Once enrolled, all youth were tested for HIV and confirmed to be HIV-negative. Results 123 youth completed the questionnaire (mean age=15 years; 63% male; 70% Hispanic). Overall, only 69 (56%) youth answered all six questions correctly. Conclusions Youth enrolled in a Hepatitis B vaccine trial demonstrated variable comprehension of the study design and various methodological concepts, such as treatment group masking. | ||
| 700 | 1 | |a Kapogiannis, G. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Flynn, M. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Rudy, J. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Bethel, James |e VerfasserIn |4 aut | |
| 700 | 1 | |a Ahmad, Sushma |e VerfasserIn |4 aut | |
| 700 | 1 | |a Tucker, Diane |e VerfasserIn |4 aut | |
| 700 | 1 | |a Abdalian, Sue Ellen |e VerfasserIn |4 aut | |
| 700 | 1 | |a Hoffman, Dannie |e VerfasserIn |4 aut | |
| 700 | 1 | |a Wilson, M. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Cunningham, K. |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Journal of medical ethics |d London : BMJ Publ., 1975 |g 39(2013), 6, Seite 410-412 |h Online-Ressource |w (DE-627)323607802 |w (DE-600)2026397-1 |w (DE-576)260773972 |x 1473-4257 |7 nnns |
| 773 | 1 | 8 | |g volume:39 |g year:2013 |g number:6 |g pages:410-412 |
| 856 | |3 Volltext |u http://www.jstor.org/stable/43282770 |x JSTOR | ||
| 856 | |u https://europepmc.org/articles/pmc3655100?pdf=render |x unpaywall |z Vermutlich kostenfreier Zugang |h repository [oa repository (via OAI-PMH doi match)] | ||
| 856 | 4 | 0 | |u https://doi.org/10.1136/medethics-2012-101286 |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u http://jme.bmj.com/content/39/6/410.abstract |x Verlag |z lizenzpflichtig |3 Volltext |
| 935 | |a mteo | ||
| 951 | |a AR | ||
| ELC | |a 1 | ||
| ITA | |a 1 |t 1 | ||
| LOK | |0 000 xxxxxcx a22 zn 4500 | ||
| LOK | |0 001 4185600097 | ||
| LOK | |0 003 DE-627 | ||
| LOK | |0 004 1816146196 | ||
| LOK | |0 005 20220908053612 | ||
| LOK | |0 008 220908||||||||||||||||ger||||||| | ||
| LOK | |0 035 |a (DE-Tue135)IxTheo#2022-08-03#A3F70A8D2CB7D9F50DF9CAABE616A0390C0575CC | ||
| LOK | |0 040 |a DE-Tue135 |c DE-627 |d DE-Tue135 | ||
| LOK | |0 092 |o n | ||
| LOK | |0 852 |a DE-Tue135 | ||
| LOK | |0 852 1 |9 00 | ||
| LOK | |0 866 |x JSTOR#http://www.jstor.org/stable/43282770 | ||
| LOK | |0 935 |a ixzs |a ixrk |a zota | ||
| OAS | |a 1 | ||
| ORI | |a SA-MARC-ixtheoa001.raw | ||