The concept of brain death did not evolve to benefit organ transplants
Although it is commonly believed that the concept of brain death (BD) was developed to benefit organ transplants, it evolved independently. Transplantation owed its development to advances in surgery and immunosuppressive treatment; BD owed its origin to the development of intensive care. The first...
Authors: | ; ; ; ; ; |
---|---|
Format: | Electronic Article |
Language: | English |
Check availability: | HBZ Gateway |
Journals Online & Print: | |
Fernleihe: | Fernleihe für die Fachinformationsdienste |
Published: |
BMJ Publ.
2007
|
In: |
Journal of medical ethics
Year: 2007, Volume: 33, Issue: 4, Pages: 197-200 |
Online Access: |
Presumably Free Access Volltext (JSTOR) Volltext (lizenzpflichtig) Volltext (lizenzpflichtig) |
MARC
LEADER | 00000caa a22000002 4500 | ||
---|---|---|---|
001 | 1816132489 | ||
003 | DE-627 | ||
005 | 20220926112709.0 | ||
007 | cr uuu---uuuuu | ||
008 | 220908s2007 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.1136/jme.2006.016931 |2 doi | |
035 | |a (DE-627)1816132489 | ||
035 | |a (DE-599)KXP1816132489 | ||
040 | |a DE-627 |b ger |c DE-627 |e rda | ||
041 | |a eng | ||
084 | |a 1 |2 ssgn | ||
100 | 1 | |a Machado, Calixto |e VerfasserIn |4 aut | |
245 | 1 | 4 | |a The concept of brain death did not evolve to benefit organ transplants |
264 | 1 | |c 2007 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a Computermedien |b c |2 rdamedia | ||
338 | |a Online-Ressource |b cr |2 rdacarrier | ||
520 | |a Although it is commonly believed that the concept of brain death (BD) was developed to benefit organ transplants, it evolved independently. Transplantation owed its development to advances in surgery and immunosuppressive treatment; BD owed its origin to the development of intensive care. The first autotransplant was achieved in the early 1900s, when studies of increased intracranial pressure causing respiratory arrest with preserved heartbeat were reported. Between 1902 and 1950, the BD concept was supported by the discovery of EEG, Crile’s definition of death, the use of EEG to demonstrate abolition of brain potentials after ischaemia, and Crafoord’s statement that death was due to cessation of blood flow. Transplantation saw the first xenotransplant in humans and the first unsuccessful kidney transplant from a cadaver. In the 1950s, circulatory arrest in coma was identified by angiography, and the death of the nervous system and coma dépassé were described. Murray performed the first successful kidney transplant. In the 1960s, the BD concept and organ transplants were instantly linked when the first kidney transplant using a brain-dead donor was performed; Schwab proposed to use EEG in BD; the Harvard Committee report and the Sydney Declaration appeared; the first successful kidney, lung and pancreas transplants using cadaveric (not brain-dead) donors were achieved; Barnard performed the first human heart transplant. This historical review demonstrates that the BD concept and organ transplantation arose separately and advanced in parallel, and only began to progress together in the late 1960s. Therefore, the BD concept did not evolve to benefit transplantation. | ||
601 | |a Transplantation | ||
700 | 1 | |a Kerein, Julius |e VerfasserIn |4 aut | |
700 | 1 | |a Ferrer, Yazmina |e VerfasserIn |4 aut | |
700 | 1 | |a Portela, Liana |e VerfasserIn |4 aut | |
700 | 1 | |a de la C García, Maria |e VerfasserIn |4 aut | |
700 | 1 | |a Manero, M. |e VerfasserIn |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Journal of medical ethics |d London : BMJ Publ., 1975 |g 33(2007), 4, Seite 197-200 |h Online-Ressource |w (DE-627)323607802 |w (DE-600)2026397-1 |w (DE-576)260773972 |x 1473-4257 |7 nnns |
773 | 1 | 8 | |g volume:33 |g year:2007 |g number:4 |g pages:197-200 |
787 | 0 | 8 | |i Errata |t CORRECTION |d 2007 |w (DE-627)1816132934 |
856 | |3 Volltext |u http://www.jstor.org/stable/27719836 |x JSTOR | ||
856 | |u https://europepmc.org/articles/pmc2652772?pdf=render |x unpaywall |z Vermutlich kostenfreier Zugang |h repository [oa repository (via OAI-PMH doi match)] | ||
856 | 4 | 0 | |u https://doi.org/10.1136/jme.2006.016931 |x Resolving-System |z lizenzpflichtig |3 Volltext |
856 | 4 | 0 | |u http://jme.bmj.com/content/33/4/197.abstract |x Verlag |z lizenzpflichtig |3 Volltext |
935 | |a mteo | ||
951 | |a AR | ||
ELC | |a 1 | ||
ITA | |a 1 |t 1 | ||
LOK | |0 000 xxxxxcx a22 zn 4500 | ||
LOK | |0 001 4185586345 | ||
LOK | |0 003 DE-627 | ||
LOK | |0 004 1816132489 | ||
LOK | |0 005 20220908053437 | ||
LOK | |0 008 220908||||||||||||||||ger||||||| | ||
LOK | |0 035 |a (DE-Tue135)IxTheo#2022-08-02#40E8D968E8CCDA139601F1E2AA4C985A67042F0E | ||
LOK | |0 040 |a DE-Tue135 |c DE-627 |d DE-Tue135 | ||
LOK | |0 092 |o n | ||
LOK | |0 852 |a DE-Tue135 | ||
LOK | |0 852 1 |9 00 | ||
LOK | |0 866 |x JSTOR#http://www.jstor.org/stable/27719836 | ||
LOK | |0 935 |a ixzs |a ixrk |a zota | ||
OAS | |a 1 | ||
ORI | |a SA-MARC-ixtheoa001.raw |