Trust based obligations of the state and physician-researchers to patient-subjects
When may a physician enroll a patient in clinical research? An adequate answer to this question requires clarification of trust-based obligations of the state and the physician-researcher respectively to the patient-subject. The state relies on the voluntarism of patient-subjects to advance the publ...
Authors: | ; |
---|---|
Format: | Electronic Article |
Language: | English |
Check availability: | HBZ Gateway |
Journals Online & Print: | |
Fernleihe: | Fernleihe für die Fachinformationsdienste |
Published: |
BMJ Publ.
2006
|
In: |
Journal of medical ethics
Year: 2006, Volume: 32, Issue: 9, Pages: 542-547 |
Online Access: |
Presumably Free Access Volltext (JSTOR) Volltext (lizenzpflichtig) Volltext (lizenzpflichtig) |
MARC
LEADER | 00000naa a22000002 4500 | ||
---|---|---|---|
001 | 181613127X | ||
003 | DE-627 | ||
005 | 20220908053430.0 | ||
007 | cr uuu---uuuuu | ||
008 | 220908s2006 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.1136/jme.2005.014670 |2 doi | |
035 | |a (DE-627)181613127X | ||
035 | |a (DE-599)KXP181613127X | ||
040 | |a DE-627 |b ger |c DE-627 |e rda | ||
041 | |a eng | ||
084 | |a 1 |2 ssgn | ||
100 | 1 | |a Miller, P. B. |e VerfasserIn |4 aut | |
245 | 1 | 0 | |a Trust based obligations of the state and physician-researchers to patient-subjects |
264 | 1 | |c 2006 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a Computermedien |b c |2 rdamedia | ||
338 | |a Online-Ressource |b cr |2 rdacarrier | ||
520 | |a When may a physician enroll a patient in clinical research? An adequate answer to this question requires clarification of trust-based obligations of the state and the physician-researcher respectively to the patient-subject. The state relies on the voluntarism of patient-subjects to advance the public interest in science. Accordingly, it is obligated to protect the agent-neutral interests of patient-subjects through promulgating standards that secure these interests. Component analysis is the only comprehensive and systematic specification of regulatory standards for benefit-harm evaluation by research ethics committees (RECs). Clinical equipoise, a standard in component analysis, ensures the treatment arms of a randomised control trial are consistent with competent medical care. It thus serves to protect agent-neutral welfare interests of the patient-subject. But REC review occurs prior to enrolment, highlighting the independent responsibility of the physician-researcher to protect the agent-relative welfare interests of the patient-subject. In a novel interpretation of the duty of care, we argue for a “clinical judgment principle” which requires the physician-researcher to exercise judgment in the interests of the patient-subject taking into account evidence on treatments and the patient-subject‘s circumstances. | ||
700 | 1 | |a Weijer, C. |e VerfasserIn |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Journal of medical ethics |d London : BMJ Publ., 1975 |g 32(2006), 9, Seite 542-547 |h Online-Ressource |w (DE-627)323607802 |w (DE-600)2026397-1 |w (DE-576)260773972 |x 1473-4257 |7 nnns |
773 | 1 | 8 | |g volume:32 |g year:2006 |g number:9 |g pages:542-547 |
856 | |3 Volltext |u http://www.jstor.org/stable/27719701 |x JSTOR | ||
856 | |u https://europepmc.org/articles/pmc2563395?pdf=render |x unpaywall |z Vermutlich kostenfreier Zugang |h repository [oa repository (via OAI-PMH doi match)] | ||
856 | 4 | 0 | |u https://doi.org/10.1136/jme.2005.014670 |x Resolving-System |z lizenzpflichtig |3 Volltext |
856 | 4 | 0 | |u http://jme.bmj.com/content/32/9/542.abstract |x Verlag |z lizenzpflichtig |3 Volltext |
935 | |a mteo | ||
936 | u | w | |d 32 |j 2006 |e 9 |h 542-547 |
951 | |a AR | ||
ELC | |a 1 | ||
ITA | |a 1 |t 1 | ||
LOK | |0 000 xxxxxcx a22 zn 4500 | ||
LOK | |0 001 4185585136 | ||
LOK | |0 003 DE-627 | ||
LOK | |0 004 181613127X | ||
LOK | |0 005 20220908053430 | ||
LOK | |0 008 220908||||||||||||||||ger||||||| | ||
LOK | |0 035 |a (DE-Tue135)IxTheo#2022-08-02#DBFAD527AE3B366844DE010A559316FE86677B07 | ||
LOK | |0 040 |a DE-Tue135 |c DE-627 |d DE-Tue135 | ||
LOK | |0 092 |o n | ||
LOK | |0 852 |a DE-Tue135 | ||
LOK | |0 852 1 |9 00 | ||
LOK | |0 866 |x JSTOR#http://www.jstor.org/stable/27719701 | ||
LOK | |0 935 |a ixzs |a ixrk |a zota | ||
OAS | |a 1 | ||
ORI | |a SA-MARC-ixtheoa001.raw |