Review of a mock research protocol in functional neuroimaging by Canadian research ethics boards

Objective: To examine how research ethics boards (REBs) review research projects in emerging disciplines such as functional neuroimaging. Design: To compare the criteria applied and the decisions reached by REBs that reviewed the same mock research protocol in functional neuroimaging. Participants:...

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Bibliographic Details
Authors: de Champlain, J. (Author) ; Patenaude, J. (Author)
Format: Electronic Article
Language:English
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Published: BMJ Publ. 2006
In: Journal of medical ethics
Year: 2006, Volume: 32, Issue: 9, Pages: 530-534
Online Access: Presumably Free Access
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520 |a Objective: To examine how research ethics boards (REBs) review research projects in emerging disciplines such as functional neuroimaging. Design: To compare the criteria applied and the decisions reached by REBs that reviewed the same mock research protocol in functional neuroimaging. Participants: 44 Canadian biomedical REBs, mostly working in public university or hospital settings. Main measurements: The mock research protocol “The Neurobiology of Social Behavior” included several ethical issues operating at all three levels: personal, institutional and social. Data consisting of responses to closed questions were analysed quantitatively. Qualitative analysis of open-question responses used mixed classification. Results: Similar criteria were used by most participating REBs. Yet the project was unconditionally approved by 3 REBs, approved conditionally by 10 and rejected by 30. Conclusions: The results point to the difficulty for REBs of reviewing all kinds of research projects, regardless of field, by relying on international and national norms framed in general terms and a possible variation between REBs in the interpretation of their mandate for the protection of research subjects. 
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