Reexamining the categorical exclusion of pediatric participants from controlled human infection trials

Controlled human infection (CHI) models have been developed for numerous pathogens in order to better understand disease processes and accelerate drug and vaccine testing. In the past, some researchers conducted highly controversial CHIs with vulnerable populations, including children. Ethical frame...

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Bibliographic Details
Authors: Murphy, Sean C. (Author) ; Duenas, Devan M. (Author) ; Richie, Thomas L. (Author) ; Shah, Seema K. (Author)
Format: Electronic Article
Language:English
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Published: Wiley-Blackwell [2020]
In: Bioethics
Year: 2020, Volume: 34, Issue: 8, Pages: 785-796
IxTheo Classification:NCH Medical ethics
NCJ Ethics of science
Further subjects:B pediatric research
B Controlled Human Infection (CHI)
B human challenge trials
B Controlled Human Malaria Infection
B research ethics
Online Access: Volltext (Verlag)
Volltext (doi)