Mitochondrial Replacement: Ethics and Identity

Mitochondrial replacement techniques (MRTs) have the potential to allow prospective parents who are at risk of passing on debilitating or even life-threatening mitochondrial disorders to have healthy children to whom they are genetically related. Ethical concerns have however been raised about these...

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Bibliographic Details
Authors: Wrigley, Anthony ca. 20./21. Jh. (Author) ; Appleby, John B. (Author) ; Wilkinson, Stephen 1965- (Author)
Format: Electronic Article
Language:English
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Published: Wiley-Blackwell [2015]
In: Bioethics
Year: 2015, Volume: 29, Issue: 9, Pages: 631-638
IxTheo Classification:NBE Anthropology
NCH Medical ethics
Further subjects:B Ethics
B Genetics
B reproductive technology
B Identity
B mitochondrial replacement
Online Access: Presumably Free Access
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520 |a Mitochondrial replacement techniques (MRTs) have the potential to allow prospective parents who are at risk of passing on debilitating or even life-threatening mitochondrial disorders to have healthy children to whom they are genetically related. Ethical concerns have however been raised about these techniques. This article focuses on one aspect of the ethical debate, the question of whether there is any moral difference between the two types of MRT proposed: Pronuclear Transfer (PNT) and Maternal Spindle Transfer (MST). It examines how questions of identity impact on the ethical evaluation of each technique and argues that there is an important difference between the two. PNT, it is argued, is a form of therapy based on embryo modification while MST is, instead, an instance of selective reproduction. The article's main ethical conclusion is that, in some circumstances, there is a stronger obligation to use PNT than MST. 
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