Vacuolar sequestration of glutathione S-conjugates outcompetes a possible degradation of the glutathione moiety by phytochelatin synthase

Monochlorobimane was used as a model xenobiotic for Arabidopsis to directly monitor the compartmentation of glutathione-bimane conjugates in situ and to quantify degradation intermediates in vitro. Vacuolar sequestration of the conjugate was very fast and outcompeted carboxypeptidation to the γ-glut...

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Bibliographic Details
Authors: Grzam, Anke (Author) ; Tennstedt, Pierre 1976- (Author) ; Clemens, Stephan 1963- (Author) ; Hell, Rüdiger (Author) ; Meyer, Andreas (Author)
Format: Electronic Article
Language:English
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Published: Wiley 3 November 2006
In: FEBS letters
Year: 2006, Volume: 580, Issue: 27, Pages: 6384-6390
Further subjects:B cysteinylglycine-bimane
B PCS
B cysteine-bimane
B GST
B Monochloro-bimane
B phytochelatin synthase
B MCB
B γ-glutamylcysteine-bimane
B glutathione S-bimane
B CysGly-B
B glutathione S-transferase
B Glutathione-conjugate degradation
B GSB
B monochlorobimane
B low molecular weight thiol
B Pi
B Cys-B
B γ-EC-B
B γ-glutamyl-transferase
B LMWT
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